Somatosensory High Frequency Oscillations reflect clinical fluctuations in migraine

Highlights ► High Frequency Oscillations (HFOs) changes were recorded in 28 migraine patients and correlated to spontaneous clinical fluctuations. ► Presynaptic HFOs were enhanced in spontaneously improved patients, whereas they were abnormally reduced in worsening ones. ► HFO recording could repres...

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Veröffentlicht in:Clinical neurophysiology 2012-10, Vol.123 (10), p.2050-2056
Hauptverfasser: Restuccia, Domenico, Vollono, Catello, Del Piero, Ivana, Martucci, Lucia, Zanini, Sergio
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Sprache:eng
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Zusammenfassung:Highlights ► High Frequency Oscillations (HFOs) changes were recorded in 28 migraine patients and correlated to spontaneous clinical fluctuations. ► Presynaptic HFOs were enhanced in spontaneously improved patients, whereas they were abnormally reduced in worsening ones. ► HFO recording could represent a useful marker to evaluate migraine progression and neurophysiological underpinnings of prophylactic drugs.
ISSN:1388-2457
1872-8952
DOI:10.1016/j.clinph.2012.03.009