Photosensitizer-incorporated G-quadruplex DNA-functionalized magnetofluorescent nanoparticles for targeted magnetic resonance/fluorescence multimodal imaging and subsequent photodynamic therapy of cancer

Photosensitizer-incorporated G-quadruplex DNA-functionalized magnetofluorescent nanoparticles for targeted magnetic resonance/fluorescence multimodal imaging and subsequent photodynamic therapy of cancer

A smart heteronanostructure has been constructed for targeted photodynamic therapy and magnetic fluorescent imaging of cancer cells using photosensitizer-incorporated G-quadruplex DNA functionalized magnetic nanoparticles.

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Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2012-01, Vol.48 (52), p.6556-6558
Hauptverfasser: Yin, Meili, Li, Zhenhua, Liu, Zhen, Ren, Jinsong, Yang, Xinjian, Qu, Xiaogang
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Breast Neoplasms - diagnosis
Breast Neoplasms - therapy
Cancer
Cell Line, Tumor
Female
Fluorescent Dyes - chemistry
Fluorescent Dyes - therapeutic use
G-Quadruplexes
Humans
Magnetic Resonance Imaging
Magnets - chemistry
Mice
Nanoparticles - chemistry
Nanoparticles - therapeutic use
Nanoparticles - ultrastructure
NIH 3T3 Cells
Photochemotherapy - methods
Photosensitizing Agents - chemistry
Photosensitizing Agents - therapeutic use
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Beschreibung
Zusammenfassung:A smart heteronanostructure has been constructed for targeted photodynamic therapy and magnetic fluorescent imaging of cancer cells using photosensitizer-incorporated G-quadruplex DNA functionalized magnetic nanoparticles.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc32129g