An eco-friendly sequential catalyst- and solvent-free four-component stereoselective synthesis of novel 1,4-pyranonaphthoquinones

A series of novel highly functionalized 1,4-pyranonaphthoquinones has been synthesized stereoselectively from one-pot sequential reactions of anilines, diethyl acetylenedicarboxylate, 2-hydroxynaphthalene-1,4-dione and benzaldehydes under microwave irradiation. This solvent- and catalyst-free transf...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Green chemistry : an international journal and green chemistry resource : GC 2012-01, Vol.14 (9), p.2484-2490
Hauptverfasser:	BALASUBRAMANIAN DEVI BALA, STEPHEN MICHAEL RAJESH, PERUMAL, Subbu
Format:	Artikel
Sprache:	eng
Schlagworte:	Catalysis Catalysts: preparations and properties Chemistry Condensed benzenic and aromatic compounds Exact sciences and technology General and physical chemistry Heterocyclic compounds Heterocyclic compounds with o, s, se, te hetero atom and condensed derivatives Noncondensed benzenic compounds Organic chemistry Preparations and properties Theory of reactions, general kinetics. Catalysis. Nomenclature, chemical documentation, computer chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A series of novel highly functionalized 1,4-pyranonaphthoquinones has been synthesized stereoselectively from one-pot sequential reactions of anilines, diethyl acetylenedicarboxylate, 2-hydroxynaphthalene-1,4-dione and benzaldehydes under microwave irradiation. This solvent- and catalyst-free transformation affording biologically relevant heterocycles presumably involves two Michael additions, aldol condensation and annulation reactions.
ISSN:	1463-9262 1463-9270
DOI:	10.1039/c2gc35930h