Challenge with a hepatitis B vaccine in two cohorts of 4–7-year-old children primed with hexavalent vaccines: An open-label, randomised trial in Italy

Challenge with a hepatitis B vaccine in two cohorts of 4–7-year-old children primed with hexavalent vaccines: An open-label, randomised trial in Italy

Highlights ► Post-challenge anti-HBs ≥10 mIU/ml occurred in >90% of all children. ► Post/pre-challenge anti-HBs GMCR were comparable in all children. ► Post-challenge anti-HBs ≥10 mIU/ml was >85% of children with

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Bibliographische Detailangaben
Veröffentlicht in:Vaccine 2012-08, Vol.30 (39), p.5770-5775
Hauptverfasser: Zanetti, Alessandro, Parlato, Antonino, Romanò, Luisa, Desole, Maria Giuseppina, Ferrera, Giuseppe, Giurdanella, Filippo, Zuliani, Massimo, Richard, Patrick, Thomas, Stéphane, Fiquet, Anne
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Antibodies
Babies
Biological products
Child
Child, Preschool
Children
confidence interval
Confidence intervals
Data processing
Diphtheria-Tetanus-acellular Pertussis Vaccines - administration & dosage
Diphtheria-Tetanus-acellular Pertussis Vaccines - immunology
Diphtheria-Tetanus-Pertussis Vaccine - administration & dosage
Diphtheria-Tetanus-Pertussis Vaccine - immunology
Haemophilus Vaccines - administration & dosage
Haemophilus Vaccines - immunology
Hepatitis
Hepatitis B
Hepatitis B Antibodies - blood
Hepatitis B challenge vaccine dose
Hepatitis B Vaccines - administration & dosage
Hepatitis B Vaccines - immunology
Hexavac
Humans
Immune memory
Immune response
Immunization
Immunologic Memory
Immunological memory
infancy
Infanrix-Hexa
Infection
Italy
Laboratories
Poliovirus Vaccine, Inactivated - administration & dosage
Poliovirus Vaccine, Inactivated - immunology
Randomised clinical trial
vaccination
Vaccines
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Zusammenfassung:Highlights ► Post-challenge anti-HBs ≥10 mIU/ml occurred in >90% of all children. ► Post/pre-challenge anti-HBs GMCR were comparable in all children. ► Post-challenge anti-HBs ≥10 mIU/ml was >85% of children with
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2012.06.078