Activity of telavancin compared to other agents against coagulase-negative staphylococci with different resistotypes by time kill

Abstract Among 10 coagulase-negative staphylococci, telavancin, quinupristin/dalfopristin, and tigecycline were the most potent antimicrobials. Telavancin exhibited bactericidal effect to 9 strains out of 10 tested at 4 × MIC after 24 h of exposure similar to those of vancomycin and daptomycin. By c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Diagnostic microbiology and infectious disease 2012-07, Vol.73 (3), p.287-289
Hauptverfasser:	Lin, Gengrong, Pankuch, Glenn A, Appelbaum, Peter C, Kosowska-Shick, Klaudia
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoglycosides - pharmacology Anti-Bacterial Agents - pharmacology Bacteriology Biological and medical sciences Coagulase - metabolism Fundamental and applied biological sciences. Psychology Humans Infectious Disease Infectious diseases Internal Medicine Medical sciences Microbial Sensitivity Tests Microbial Viability - drug effects Microbiology Miscellaneous Staphylococcus - drug effects Staphylococcus - enzymology Staphylococcus aureus Telavancin Time Factors Time kill
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Abstract Among 10 coagulase-negative staphylococci, telavancin, quinupristin/dalfopristin, and tigecycline were the most potent antimicrobials. Telavancin exhibited bactericidal effect to 9 strains out of 10 tested at 4 × MIC after 24 h of exposure similar to those of vancomycin and daptomycin. By contrast, linezolid was mainly bacteriostatic and teicoplanin was bactericidal to 7 strains tested at 4 × MIC after 24 h.
ISSN:	0732-8893 1879-0070
DOI:	10.1016/j.diagmicrobio.2012.04.003