Fluorescence sensing of caffeine in aqueous solution with carbazole-based probe and imaging application in live cells
The host–guest interaction of caffeine in aqueous solutions has been achieved by using carbazole based imino-phenol receptors with oxopurines influences their fluorescence properties and can be exploited for ‘turn-ON’ fluorescence sensing of caffeine. This new fluorescent probe with high sensitivity...
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| Veröffentlicht in: | Bioorganic & medicinal chemistry letters 2012-09, Vol.22 (17), p.5379-5383 |
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| container_end_page | 5383 |
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| container_issue | 17 |
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| container_title | Bioorganic & medicinal chemistry letters |
| container_volume | 22 |
| creator | Mahapatra, Ajit Kumar Roy, Jagannath Sahoo, Prithidipa Mukhopadhyay, Subhra Kanti Mukhopadhyay, Anindita Roy Mandal, Debasish |
| description | The host–guest interaction of caffeine in aqueous solutions has been achieved by using carbazole based imino-phenol receptors with oxopurines influences their fluorescence properties and can be exploited for ‘turn-ON’ fluorescence sensing of caffeine. This new fluorescent probe with high sensitivity and selectivity for detection and first time imaging of caffeine in living cells was developed in aqueous media. |
| doi_str_mv | 10.1016/j.bmcl.2012.07.055 |
| format | Article |
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This new fluorescent probe with high sensitivity and selectivity for detection and first time imaging of caffeine in living cells was developed in aqueous media.</description><identifier>ISSN: 0960-894X</identifier><identifier>EISSN: 1464-3405</identifier><identifier>DOI: 10.1016/j.bmcl.2012.07.055</identifier><identifier>PMID: 22877628</identifier><language>eng</language><publisher>Amsterdam: Elsevier Ltd</publisher><subject>aqueous solutions ; Biological and medical sciences ; Caffeine ; Caffeine - analysis ; Candida albicans ; Candida albicans - cytology ; Carbazole ; Carbazoles - chemistry ; Cell Survival ; Computed tomography ; Fluorescence ; Fluorescent Dyes - chemistry ; Fluorescent indicators ; image analysis ; Medical sciences ; Microscopy, Fluorescence - methods ; Models, Molecular ; Pharmacology. 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All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c443t-a68e5f67f312d52775d95ff9d572bb31eeb2dbeac7b1f0f26eecf93c519f0ab43</citedby><cites>FETCH-LOGICAL-c443t-a68e5f67f312d52775d95ff9d572bb31eeb2dbeac7b1f0f26eecf93c519f0ab43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0960894X12009316$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26340339$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22877628$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mahapatra, Ajit Kumar</creatorcontrib><creatorcontrib>Roy, Jagannath</creatorcontrib><creatorcontrib>Sahoo, Prithidipa</creatorcontrib><creatorcontrib>Mukhopadhyay, Subhra Kanti</creatorcontrib><creatorcontrib>Mukhopadhyay, Anindita Roy</creatorcontrib><creatorcontrib>Mandal, Debasish</creatorcontrib><title>Fluorescence sensing of caffeine in aqueous solution with carbazole-based probe and imaging application in live cells</title><title>Bioorganic & medicinal chemistry letters</title><addtitle>Bioorg Med Chem Lett</addtitle><description>The host–guest interaction of caffeine in aqueous solutions has been achieved by using carbazole based imino-phenol receptors with oxopurines influences their fluorescence properties and can be exploited for ‘turn-ON’ fluorescence sensing of caffeine. This new fluorescent probe with high sensitivity and selectivity for detection and first time imaging of caffeine in living cells was developed in aqueous media.</description><subject>aqueous solutions</subject><subject>Biological and medical sciences</subject><subject>Caffeine</subject><subject>Caffeine - analysis</subject><subject>Candida albicans</subject><subject>Candida albicans - cytology</subject><subject>Carbazole</subject><subject>Carbazoles - chemistry</subject><subject>Cell Survival</subject><subject>Computed tomography</subject><subject>Fluorescence</subject><subject>Fluorescent Dyes - chemistry</subject><subject>Fluorescent indicators</subject><subject>image analysis</subject><subject>Medical sciences</subject><subject>Microscopy, Fluorescence - methods</subject><subject>Models, Molecular</subject><subject>Pharmacology. Drug treatments</subject><subject>Receptor mechanisms</subject><subject>receptors</subject><subject>Sensitivity and Specificity</subject><subject>Spectrometry, Fluorescence - methods</subject><subject>Water - chemistry</subject><subject>Xanthine alkaloid</subject><subject>‘Turn-ON’ fluorescent probe</subject><issn>0960-894X</issn><issn>1464-3405</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkc1u1DAURi0EotPCC7AAb5C6SfB_EolNVVFAqsQCKrGzbOd68MgTD3ZSBE-PwwywQ6y8Offzd-9B6BklLSVUvdq1du9iywhlLelaIuUDtKFCiYYLIh-iDRkUafpBfD5D56XsCKGCCPEYnTHWd51i_QYtN3FJGYqDyQEuMJUwbXHy2BnvIUyAw4TN1wXSUnBJcZlDmvC3MH-pRLbmR4rQWFNgxIecLGAzjTjszXaNMYdDDM78GqkxMdwDdhBjeYIeeRMLPD29F-ju5s2n63fN7Ye376-vbhsnBJ8bo3qQXnWeUzZK1nVyHKT3wyg7Zi2nAJaNFozrLPXEMwXg_MCdpIMnxgp-gS6PubVb3aHMeh_K2sBM60KaEt7LYaD0v1AhKScdrSg7oi6nUjJ4fch15fy9Qno1o3d6NaNXM5p0upqpQ89P-Yvdw_hn5LeKCrw8AaY4E302kwvlL6eqVM6Hyr04ct4kbba5Mncf60-y6uWUKFWJ10cC6mnvA2RdXFj9jiGDm_WYwr-a_gSDc7d3</recordid><startdate>20120901</startdate><enddate>20120901</enddate><creator>Mahapatra, Ajit Kumar</creator><creator>Roy, Jagannath</creator><creator>Sahoo, Prithidipa</creator><creator>Mukhopadhyay, Subhra Kanti</creator><creator>Mukhopadhyay, Anindita Roy</creator><creator>Mandal, Debasish</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20120901</creationdate><title>Fluorescence sensing of caffeine in aqueous solution with carbazole-based probe and imaging application in live cells</title><author>Mahapatra, Ajit Kumar ; Roy, Jagannath ; Sahoo, Prithidipa ; Mukhopadhyay, Subhra Kanti ; Mukhopadhyay, Anindita Roy ; Mandal, Debasish</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c443t-a68e5f67f312d52775d95ff9d572bb31eeb2dbeac7b1f0f26eecf93c519f0ab43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>aqueous solutions</topic><topic>Biological and medical sciences</topic><topic>Caffeine</topic><topic>Caffeine - analysis</topic><topic>Candida albicans</topic><topic>Candida albicans - cytology</topic><topic>Carbazole</topic><topic>Carbazoles - chemistry</topic><topic>Cell Survival</topic><topic>Computed tomography</topic><topic>Fluorescence</topic><topic>Fluorescent Dyes - chemistry</topic><topic>Fluorescent indicators</topic><topic>image analysis</topic><topic>Medical sciences</topic><topic>Microscopy, Fluorescence - methods</topic><topic>Models, Molecular</topic><topic>Pharmacology. 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| identifier | ISSN: 0960-894X |
| ispartof | Bioorganic & medicinal chemistry letters, 2012-09, Vol.22 (17), p.5379-5383 |
| issn | 0960-894X 1464-3405 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | aqueous solutions Biological and medical sciences Caffeine Caffeine - analysis Candida albicans Candida albicans - cytology Carbazole Carbazoles - chemistry Cell Survival Computed tomography Fluorescence Fluorescent Dyes - chemistry Fluorescent indicators image analysis Medical sciences Microscopy, Fluorescence - methods Models, Molecular Pharmacology. Drug treatments Receptor mechanisms receptors Sensitivity and Specificity Spectrometry, Fluorescence - methods Water - chemistry Xanthine alkaloid ‘Turn-ON’ fluorescent probe |
| title | Fluorescence sensing of caffeine in aqueous solution with carbazole-based probe and imaging application in live cells |
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