Histological assessment of impact of ovarian endometrioma and laparoscopic cystectomy on ovarian reserve

Aim: The rate of oocyte decline follows a biphasic pattern, characterized by acceleration between 32 and 38 years old. Ovarian reserve is also affected by external factors, including ovarian disease and iatrogenic damage. The aim of this study was to histologically evaluate the impact of ovarian endometriomas, laparoscopic cystectomy, and age on follicle reserve in healthy ovarian tissues and in surgically resected cyst walls. Material and Methods: Sixty‐one patients were found to have ovarian endometriomas and 42 patients non‐endometriotic cysts. A small amount of normal ovarian tissue was obtained during ovarian cystectomy. The follicles in normal ovarian tissue and resected cyst walls were histologically evaluated. Results: The density of follicles in ovarian tissues correlated with the age of the patients in both groups. In women aged