Symptoms of sleep apnoea in chronic heart failure—results from a prospective cohort study in 1,500 patients

Background In patients with chronic heart failure, sleep-disordered breathing (SDB) is a common co-morbidity worsening prognosis. The aim of this study was to investigate whether assessment of specific symptoms can elucidate presence of SDB in these patients. Methods A prospective questionnaire scor...

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Veröffentlicht in:	Sleep & breathing 2012-09, Vol.16 (3), p.781-791
Hauptverfasser:	Bitter, Thomas, Westerheide, Nina, Hossain, Sajid Mohammed, Prinz, Christian, Horstkotte, Dieter, Oldenburg, Olaf
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Body Mass Index Cheyne-Stokes Respiration - diagnosis Cheyne-Stokes Respiration - epidemiology Chronic illnesses Cohort Studies Comorbidity Cross-Sectional Studies Dentistry Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes Echocardiography Female Fundamental and applied biological sciences. Psychology Germany Health Surveys Heart failure Heart Failure - diagnosis Heart Failure - epidemiology Humans Internal Medicine Male Mass Screening Medical sciences Medicine Medicine & Public Health Middle Aged Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Nervous system (semeiology, syndromes) Neurology Original Article Otorhinolaryngology Patients Pediatrics Pneumology/Respiratory System Polysomnography Prospective Studies Risk Factors Sex Factors Sleep apnea Sleep Apnea Syndromes - diagnosis Sleep Apnea Syndromes - epidemiology Sleep Apnea, Central - diagnosis Sleep Apnea, Central - epidemiology Sleep Apnea, Obstructive - diagnosis Sleep Apnea, Obstructive - epidemiology Sleep. Vigilance Surveys and Questionnaires Vertebrates: nervous system and sense organs
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Zusammenfassung:	Background In patients with chronic heart failure, sleep-disordered breathing (SDB) is a common co-morbidity worsening prognosis. The aim of this study was to investigate whether assessment of specific symptoms can elucidate presence of SDB in these patients. Methods A prospective questionnaire scoring investigation on possible symptoms of sleep apnoea (nocturia, fatigue, daytime sleepiness, snoring, nocturnal sweating, witnessed apnoea’s, nap) was conducted in 1,506 consecutive patients with stable chronic heart failure (LVEF ≤45%, NYHA ≥2). Afterwards, polysomnography or polygraphy, capillary blood gas analysis, echocardiography, and cardiopulmonary exercise testing were performed. Results Adjusted for all significant covariates, snoring ( p
ISSN:	1520-9512 1522-1709
DOI:	10.1007/s11325-011-0575-0