Regional gray matter changes in obsessiveacompulsive disorder: Relationship to clinical characteristics

Regional gray matter changes in obsessiveacompulsive disorder: Relationship to clinical characteristics

Regional brain volumes were compared between 23 participants with obsessiveacompulsive disorder (OCD) and 36 healthy controls using magnetic resonance imaging with voxel-based morphometry. A volumetric decrease in OCD was found in the right mediofrontal cortex. An increase was found in the left temp...

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Veröffentlicht in:Psychiatry research. Neuroimaging 2012-04, Vol.202 (1), p.74-76
Hauptverfasser: Exner, Cornelia, Zetsche, Ulrike, Martin, Vera, Rief, Winfried, Jansen, Andreas
Format: Artikel
Sprache:eng
Schlagworte:
Age
Cortex
Magnetic resonance imaging
Morphometry
Neuroimaging
Obsessive compulsive disorder
Substantia grisea
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Zusammenfassung:Regional brain volumes were compared between 23 participants with obsessiveacompulsive disorder (OCD) and 36 healthy controls using magnetic resonance imaging with voxel-based morphometry. A volumetric decrease in OCD was found in the right mediofrontal cortex. An increase was found in the left temporoparietal cortex. Volume alterations were related to symptom severity and age of onset.
ISSN:0925-4927
DOI:10.1016/j.pscychresns.2011.10.007