Multidrug-resistant clones of community-associated meticillin-resistant Staphylococcus aureus isolated from Chinese children and the resistance genes to clindamycin and mupirocin

This study aimed to correlate the multidrug resistance (MDR) and sequence type (ST) clones of community-associated (CA) meticillin-resistant Staphylococcus aureus (MRSA) to identify the genes responsible for clindamycin and mupirocin resistance in S. aureus isolates from paediatric hospitals in main...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of medical microbiology 2012-09, Vol.61 (9), p.1240-1247
Hauptverfasser:	Wang, Lijuan, Liu, Yingchao, Yang, Yonghong, Huang, Guoying, Wang, Chuanqing, Deng, Li, Zheng, Yuejie, Fu, Zhou, Li, Changcong, Shang, Yunxiao, Zhao, Changan, Sun, Mingjiao, Li, Xiangmei, Yu, Sangjie, Yao, Kaihu, Shen, Xuzhuang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Anti-Bacterial Agents - pharmacology Bacteriology Biological and medical sciences Child Child, Preschool China Clindamycin - pharmacology Community-Acquired Infections - microbiology Drug Resistance, Multiple, Bacterial - genetics Fundamental and applied biological sciences. Psychology Humans Infant Infant, Newborn Infectious diseases Medical sciences Methicillin-Resistant Staphylococcus aureus - drug effects Methicillin-Resistant Staphylococcus aureus - genetics Methicillin-Resistant Staphylococcus aureus - isolation & purification Methicillin-Resistant Staphylococcus aureus - metabolism Microbial Sensitivity Tests Microbiology Miscellaneous Mupirocin - pharmacology Sequence Analysis, DNA Staphylococcal Infections - microbiology Staphylococcus aureus - drug effects Staphylococcus aureus - genetics Staphylococcus aureus - isolation & purification Staphylococcus aureus - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	This study aimed to correlate the multidrug resistance (MDR) and sequence type (ST) clones of community-associated (CA) meticillin-resistant Staphylococcus aureus (MRSA) to identify the genes responsible for clindamycin and mupirocin resistance in S. aureus isolates from paediatric hospitals in mainland China. A total of 435 S. aureus isolates were collected. Compared with CA meticillin-susceptible S. aureus (MSSA), the resistance rates of CA-MRSA to ciprofloxacin, chloramphenicol, gentamicin and tetracycline were higher (19.0 vs 2.6 %, P
ISSN:	0022-2615 1473-5644
DOI:	10.1099/jmm.0.042663-0