Osteosarcoma of the femur mimicking Ewing sarcoma/primitive neuroectodermal tumour on biopsy and metastatic carcinoma on resection
Osteosarcoma (OS) is known to have several morphological appearances, small cell osteosarcoma and epithelioid osteosarcoma being two well recognized patterns. The former can be mistaken for a Ewing sarcoma/primitive neuroectodermal tumour (ES/PNET), whereas the latter mimics metastatic carcinoma. He...
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Veröffentlicht in: | Skeletal radiology 2012-09, Vol.41 (9), p.1163-1168 |
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description | Osteosarcoma (OS) is known to have several morphological appearances, small cell osteosarcoma and epithelioid osteosarcoma being two well recognized patterns. The former can be mistaken for a Ewing sarcoma/primitive neuroectodermal tumour (ES/PNET), whereas the latter mimics metastatic carcinoma. Herein we present an osteosarcoma in a 17-year-old girl that was diagnosed as an ES/PNET on biopsy; however, the resected specimen revealed a very unusual morphology mimicking a metastatic carcinoma with a sex cord stromal tumour-like pattern. |
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The former can be mistaken for a Ewing sarcoma/primitive neuroectodermal tumour (ES/PNET), whereas the latter mimics metastatic carcinoma. 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The former can be mistaken for a Ewing sarcoma/primitive neuroectodermal tumour (ES/PNET), whereas the latter mimics metastatic carcinoma. 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pathology</topic><topic>Carcinoma, Neuroendocrine - secondary</topic><topic>Carcinoma, Neuroendocrine - surgery</topic><topic>Case Report</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>Femoral Neoplasms - diagnosis</topic><topic>Humans</topic><topic>Imaging</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metastasis</topic><topic>Nuclear Medicine</topic><topic>Orthopedics</topic><topic>Osteosarcoma</topic><topic>Osteosarcoma - diagnosis</topic><topic>Pathology</topic><topic>Radiology</topic><topic>Sarcoma, Ewing - pathology</topic><topic>Sarcoma, Ewing - secondary</topic><topic>Sarcoma, Ewing - surgery</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jambhekar, Nirmala Ajit</creatorcontrib><creatorcontrib>Agarwal, Manish</creatorcontrib><creatorcontrib>Suryawanshi, Pallavi</creatorcontrib><creatorcontrib>Desai, Saral</creatorcontrib><creatorcontrib>Rekhi, Bharat</creatorcontrib><creatorcontrib>Gulia, Ashish</creatorcontrib><creatorcontrib>Puri, Ajay</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - 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The former can be mistaken for a Ewing sarcoma/primitive neuroectodermal tumour (ES/PNET), whereas the latter mimics metastatic carcinoma. Herein we present an osteosarcoma in a 17-year-old girl that was diagnosed as an ES/PNET on biopsy; however, the resected specimen revealed a very unusual morphology mimicking a metastatic carcinoma with a sex cord stromal tumour-like pattern.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>22565380</pmid><doi>10.1007/s00256-012-1406-5</doi><tpages>6</tpages></addata></record> |
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subjects | Adolescent Cancer Carcinoma Carcinoma, Neuroendocrine - pathology Carcinoma, Neuroendocrine - secondary Carcinoma, Neuroendocrine - surgery Case Report Diagnosis, Differential Female Femoral Neoplasms - diagnosis Humans Imaging Medicine Medicine & Public Health Metastasis Nuclear Medicine Orthopedics Osteosarcoma Osteosarcoma - diagnosis Pathology Radiology Sarcoma, Ewing - pathology Sarcoma, Ewing - secondary Sarcoma, Ewing - surgery Surgery |
title | Osteosarcoma of the femur mimicking Ewing sarcoma/primitive neuroectodermal tumour on biopsy and metastatic carcinoma on resection |
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