Osteosarcoma of the femur mimicking Ewing sarcoma/primitive neuroectodermal tumour on biopsy and metastatic carcinoma on resection

Osteosarcoma (OS) is known to have several morphological appearances, small cell osteosarcoma and epithelioid osteosarcoma being two well recognized patterns. The former can be mistaken for a Ewing sarcoma/primitive neuroectodermal tumour (ES/PNET), whereas the latter mimics metastatic carcinoma. He...

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Veröffentlicht in:	Skeletal radiology 2012-09, Vol.41 (9), p.1163-1168
Hauptverfasser:	Jambhekar, Nirmala Ajit, Agarwal, Manish, Suryawanshi, Pallavi, Desai, Saral, Rekhi, Bharat, Gulia, Ashish, Puri, Ajay
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Cancer Carcinoma Carcinoma, Neuroendocrine - pathology Carcinoma, Neuroendocrine - secondary Carcinoma, Neuroendocrine - surgery Case Report Diagnosis, Differential Female Femoral Neoplasms - diagnosis Humans Imaging Medicine Medicine & Public Health Metastasis Nuclear Medicine Orthopedics Osteosarcoma Osteosarcoma - diagnosis Pathology Radiology Sarcoma, Ewing - pathology Sarcoma, Ewing - secondary Sarcoma, Ewing - surgery Surgery
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Zusammenfassung:	Osteosarcoma (OS) is known to have several morphological appearances, small cell osteosarcoma and epithelioid osteosarcoma being two well recognized patterns. The former can be mistaken for a Ewing sarcoma/primitive neuroectodermal tumour (ES/PNET), whereas the latter mimics metastatic carcinoma. Herein we present an osteosarcoma in a 17-year-old girl that was diagnosed as an ES/PNET on biopsy; however, the resected specimen revealed a very unusual morphology mimicking a metastatic carcinoma with a sex cord stromal tumour-like pattern.
ISSN:	0364-2348 1432-2161
DOI:	10.1007/s00256-012-1406-5