Brucellosis as a trigger agent for Henoch-Schönlein purpura

Vasculitis in childhood is a result of a spectrum of causes ranging from idiopathic conditions with primary vessel inflammation to syndromes after exposure to recognized antigenic triggers, such as infectious agents and drugs causing hypersensitivity reactions. Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood. Although there is often a history of a recent or simultaneous upper respiratory tract infection, no consistent causative organism is found. We report an 11-year old boy with HSP and brucellosis and we speculated that brucellosis was the trigger agent for HSP (Ref. 13). brucellosis, trigger agent, Henoch-Schönlein purpura, vasculitis, infectious agents, drug, hypersensitivity reactions, primary vessel inflammation.