Right Hepatectomy in Patients over 70 Years of Age: An Analysis of Liver Function and Outcome

Background As a consequence of the increase in life expectancy, hepatobiliary surgeons have to deal with an emerging aged population. We aimed to analyze the liver function and outcome after right hepatectomy (RH) in patients over 70 years of age. Methods From January 2006 to December 2009, we prosp...

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Veröffentlicht in:World journal of surgery 2012-09, Vol.36 (9), p.2161-2170
Hauptverfasser: Melloul, Emmanuel, Halkic, Nermin, Raptis, Dimitri Aristotle, Tempia, Adrien, Demartines, Nicolas
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Sprache:eng
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Zusammenfassung:Background As a consequence of the increase in life expectancy, hepatobiliary surgeons have to deal with an emerging aged population. We aimed to analyze the liver function and outcome after right hepatectomy (RH) in patients over 70 years of age. Methods From January 2006 to December 2009, we prospectively collected data of 207 consecutive elective hepatectomies. In patients who had RH, cardiac risk was assessed by a dedicated preoperative workup. Liver failure (LF) was defined by the “fifty–fifty” criteria at postoperative day 5 (POD) and morbidity by the Clavien–Dindo classification. Liver function tests (LFTs) and short-term outcome were retrospectively analyzed in patients over (elderly group, EG) and younger (young group, YG) than 70 years of age. Results Eighty-seven consecutive RH were performed during the study period. Indication for surgery included 90 % malignancy in 47 % of patients requiring preoperative chemotherapy. ASA grade > 2 (44 vs. 16 %, p  = 0.027), ischemic heart disease (17 vs. 5 %, p  = 0.076), and preoperative cardiac failure (26 vs. 2 %, p  
ISSN:0364-2313
1432-2323
DOI:10.1007/s00268-012-1621-1