Gonadotropin signalling in epithelial ovarian cancer

Ovarian cancer is the most lethal of all gynecologic malignancies, although its aetiology remains poorly understood. A role for the gonadotropins, follicle-stimulating hormone (FSH) and luteinising hormone (LH), has been implicated in a variety of different aspects of ovarian cancer tumorigenesis, i...

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Veröffentlicht in:	Cancer letters 2012-11, Vol.324 (2), p.152-159
Hauptverfasser:	Mertens-Walker, Inga, Baxter, Robert C, Marsh, Deborah J
Format:	Artikel
Sprache:	eng
Schlagworte:	animal ovaries Animals Antineoplastic Agents, Hormonal - metabolism Antineoplastic Agents, Hormonal - therapeutic use carcinogenesis Carcinoma, Ovarian Epithelial cell proliferation etiology Female Follicle Stimulating Hormone - metabolism follicle-stimulating hormone FSH gene expression Gonadotropins Gonadotropins - genetics Gonadotropins - metabolism Hematology, Oncology and Palliative Medicine Humans Infertility Ligands luteinizing hormone Luteinizing Hormone - metabolism Medical research Menopause Mortality Neoplasms, Glandular and Epithelial - drug therapy Neoplasms, Glandular and Epithelial - genetics Neoplasms, Glandular and Epithelial - metabolism Neoplasms, Glandular and Epithelial - pathology Ovarian cancer ovarian neoplasms Ovarian Neoplasms - drug therapy Ovarian Neoplasms - genetics Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology Receptors, Gonadotropin - metabolism Signal Transduction - drug effects Signalling pathways Studies
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