Proinflammatory and oxidative stress markers in patients submitted to Roux-en-Y gastric bypass after 1 year of follow-up

BACKGROUND/OBJECTIVES: This study examined the effect of weight loss after 3, 6 and 12 months of Roux-en-Y Gastric Bypass (RYGB) on energy intake and on several biomarkers of oxidative stress such as levels of vitamin C, beta-carotene, vitamin E (diet/blood), nitric oxide metabolites (NOx), myeloper...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of clinical nutrition 2012-08, Vol.66 (8), p.891-899
Hauptverfasser:	da Silva, V R G, Moreira, E A M, Wilhelm-Filho, D, de Miranda, J X, Benincá, J P, Vigil, S V G, Moratelli, A M B, Garlet, T R, de Souza Meirelles, M S, Vannucchi, H, Fröde, T S
Format:	Artikel
Sprache:	eng
Schlagworte:	692/53 692/700/459/1994 692/700/565/545/2098 Adult Antioxidants Antioxidants - administration & dosage Ascorbic acid Ascorbic Acid - administration & dosage Ascorbic Acid - blood beta Carotene - administration & dosage beta Carotene - blood Biological and medical sciences Biomarkers Biomarkers - blood Blood Body Mass Index Body size Body weight Body weight loss Carotene Case-Control Studies Catalase Catalase - blood Clinical Nutrition Complications and side effects Development and progression Diet Dietary Supplements Energy Intake Epidemiology Feeding. Feeding behavior Female Follow-Up Studies Fundamental and applied biological sciences. Psychology Gastric bypass Gastric Bypass - methods Gastrointestinal surgery Glutathione Glutathione - blood Health aspects Humans Inflammation Inflammation - physiopathology Inflammation - therapy Internal Medicine Male Medical sciences Medicine Medicine & Public Health Metabolic Diseases Metabolites Middle Aged Nitric oxide Obesity original-article Oxidative Stress Peroxidase Peroxidase - blood Physiological aspects Prospective Studies Public Health Stomach, duodenum, intestine, rectum, anus Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system Thiobarbituric acid Thiobarbituric Acid Reactive Substances - analysis Thiobarbituric Acid Reactive Substances - metabolism Tocopherol Vertebrates: anatomy and physiology, studies on body, several organs or systems Vitamin C Vitamin E Vitamin E - administration & dosage Vitamin E - blood Vitamins Weight Loss β-Carotene
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	BACKGROUND/OBJECTIVES: This study examined the effect of weight loss after 3, 6 and 12 months of Roux-en-Y Gastric Bypass (RYGB) on energy intake and on several biomarkers of oxidative stress such as levels of vitamin C, beta-carotene, vitamin E (diet/blood), nitric oxide metabolites (NOx), myeloperoxidase (MPO), thiobarbituric acid reactive substances (TBARS), reduced glutathione (GSH) and activity of catalase (CAT). SUBJECTS/METHODS: Study with a control group (CG), assessed once, and a bariatric group (BG) assessed at the basal period as well as at 3, 6 and 12 months post-surgery; both groups were composed of 5 men and 31 women ( n =36). Age was 38.7±9.4 and 39.6±9.2 years old and body mass index (BMI) was 22.2±2.1 and 47.6±9.1 kg/m 2 , respectively. The variance measure quoted was SEM. RESULTS: The body weight at 12 months was 35.8±1.0% ( P
ISSN:	0954-3007 1476-5640
DOI:	10.1038/ejcn.2012.17