Pregnancy Outcome in Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune disorder resulting in neurologic and psychiatric symptoms. Treatment is challenging in pregnancy, because little data exist to guide management. A 24-year-old woman with a known diagnosis of anti-NMDA receptor encephalitis using...
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Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 2012-08, Vol.120 (Suppl 2), p.480-483 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune disorder resulting in neurologic and psychiatric symptoms. Treatment is challenging in pregnancy, because little data exist to guide management.
A 24-year-old woman with a known diagnosis of anti-NMDA receptor encephalitis using intravenous immunoglobulin therapy became pregnant. Her pregnancy was uncomplicated with no relapses. She delivered at 35 4/7 weeks of gestation after having preterm premature rupture of membranes. She had a relapse of symptoms after delivery.
This patient with anti-NMDA receptor encephalitis had an uneventful pregnancy with overall good outcome; however, she experienced relapse soon after delivery. This disease may mimic other autoimmune diseases, with improvement during pregnancy and risk for relapse postpartum. |
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ISSN: | 0029-7844 1873-233X |
DOI: | 10.1097/AOG.0b013e31825935d4 |