Nonbismuth Quadruple (Concomitant) Therapy: Empirical and Tailored Efficacy versus Standard Triple Therapy for Clarithromycin-Susceptible Helicobacter pylori and versus Sequential Therapy for Clarithromycin-Resistant Strains

Nonbismuth Quadruple (Concomitant) Therapy: Empirical and Tailored Efficacy versus Standard Triple Therapy for Clarithromycin-Susceptible Helicobacter pylori and versus Sequential Therapy for Clarithromycin-Resistant Strains

Background:  Using quadruple clarithromycin‐containing regimens for Helicobacter pylori eradication is controversial with high rates of macrolide resistance. Aim:  To evaluate antibiotic resistance rates and the efficacy of empirical and tailored nonbismuth quadruple (concomitant) therapy in a setti...

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Veröffentlicht in:Helicobacter (Cambridge, Mass.) Mass.), 2012-08, Vol.17 (4), p.269-276
Hauptverfasser: Molina-Infante, Javier, Pazos-Pacheco, Carmen, Vinagre-Rodriguez, Gema, Perez-Gallardo, Belen, Dueñas-Sadornil, Carmen, Hernandez-Alonso, Moisés, Gonzalez-Garcia, Guadalupe, Mateos-Rodriguez, Jose M., Fernandez-Bermejo, Miguel, Gisbert, Javier P.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Aged
Aged, 80 and over
Amoxicillin - therapeutic use
Anti-Bacterial Agents - therapeutic use
Clarithromycin - therapeutic use
clarithromycin resistance
concomitant therapy
Drug Resistance, Bacterial
Drug Therapy, Combination
Female
Helicobacter Infections - drug therapy
Helicobacter Infections - microbiology
Helicobacter pylori
Helicobacter pylori - drug effects
Helicobacter pylori - physiology
Humans
Male
Metronidazole - therapeutic use
Middle Aged
nonbismuth quadruple therapy
Proton Pump Inhibitors - therapeutic use
sequential therapy
triple therapy
Young Adult
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Zusammenfassung:Background:  Using quadruple clarithromycin‐containing regimens for Helicobacter pylori eradication is controversial with high rates of macrolide resistance. Aim:  To evaluate antibiotic resistance rates and the efficacy of empirical and tailored nonbismuth quadruple (concomitant) therapy in a setting with cure rates
ISSN:1083-4389
1523-5378
DOI:10.1111/j.1523-5378.2012.00947.x