Determination of the Absolute Configuration of 19-OH-(-)-Eburnamonine Using a Combination of Residual Dipolar Couplings, DFT Chemical Shift Predictions, and Chiroptics

Determination of the Absolute Configuration of 19-OH-(-)-Eburnamonine Using a Combination of Residual Dipolar Couplings, DFT Chemical Shift Predictions, and Chiroptics

19-OH-(-)-eburnamonine 1 is a new indole alkaloid isolated from Bonafusia macrocalyx. A natural derivative from (-)-eburnamonine for which absolute configuration and conformation has been determined by making use of residual dipolar couplings enhanced NMR, circular dichroism spectra and high-level c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Natural product communications 2012-06, Vol.7 (6), p.735-738
Hauptverfasser: Trigo-Mouriño, Pablo, Sifuentes, Roxana, Navarro-Vázquez, Armando, Gayathri, Chakicherla, Maruenda, Helena, Gil, Roberto R.
Format: Artikel
Sprache:eng
Schlagworte:
Models, Molecular
Molecular Conformation
Nuclear Magnetic Resonance, Biomolecular - methods
Vinca Alkaloids - chemistry
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:19-OH-(-)-eburnamonine 1 is a new indole alkaloid isolated from Bonafusia macrocalyx. A natural derivative from (-)-eburnamonine for which absolute configuration and conformation has been determined by making use of residual dipolar couplings enhanced NMR, circular dichroism spectra and high-level computations.
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X1200700611