Structural deterioration of the cryopreserved mitral homograft valve

Objective The aim of this study was to evaluate the long-term fate of the cryopreserved mitral homograft focusing on structural valve deterioration. Methods Homograft replacement of the mitral valve was performed in 106 patients. The causes of mitral disease were rheumatic disease (n = 75), endocard...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2012-08, Vol.144 (2), p.313-320.e1
Hauptverfasser:	Olivito, Silvio, MD, Lalande, Stéphanie, MD, Nappi, Francesco, MD, Hammoudi, Nadjib, MD, D’Alessandro, Cosimo, MD, Fouret, Pierre, MD, Acar, Christophe, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bioprosthesis Cardiology. Vascular system Cardiothoracic Surgery Child Cryopreservation Endocarditis, Bacterial - complications Female Heart Valve Diseases - surgery Heart Valve Prosthesis Humans Male Medical sciences Middle Aged Mitral Valve - transplantation Mitral Valve Stenosis - surgery Pneumology Pregnancy Pregnancy Complications, Cardiovascular - surgery Reoperation Rheumatic Heart Disease - complications Transplantation, Homologous Young Adult
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Zusammenfassung:	Objective The aim of this study was to evaluate the long-term fate of the cryopreserved mitral homograft focusing on structural valve deterioration. Methods Homograft replacement of the mitral valve was performed in 106 patients. The causes of mitral disease were rheumatic disease (n = 75), endocarditis (n = 24), and others (n = 7). There were 40 partial homografts and 66 total homografts. Results Mean follow-up was 9.3 + 4.7 years (up to 17.8 years). There were 5 early (
ISSN:	0022-5223 1097-685X
DOI:	10.1016/j.jtcvs.2011.06.041