Psychoimmune Interactions in Women of Reproductive Age with Endometriosis

Psychoimmune Interactions in Women of Reproductive Age with Endometriosis

Psychoimmune interactions were studied in women of reproductive age with endometriosis. Pronounced immunological shifts manifested in a shift of the T-cellular immunity, resulting in imbalanced production of pro- (IL-1β, IL-2, IFN-γ) and anti-inflammatory (IL-4) cytokines. Significant correlations b...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2011-11, Vol.152 (1), p.93-97
Hauptverfasser: Nasyrova, R. F., Sotnikova, L. S., Baystrukova, N. V., Krivoschchekova, G. V., Novitsky, V. V., Kupriyanova, I. E., Semke, V. Ya, Naslednikova, I. O., Baykov, A. N.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Antigens, CD - metabolism
Anxiety - blood
Anxiety - epidemiology
Anxiety - immunology
Biomedical and Life Sciences
Biomedicine
Case-Control Studies
Cell Biology
Comorbidity
Cytokines - blood
Depression - blood
Depression - epidemiology
Depression - immunology
Development and progression
Endometriosis
Endometriosis - blood
Endometriosis - epidemiology
Endometriosis - immunology
Endometriosis - psychology
Female
Health aspects
Humans
Internal Medicine
Laboratory Medicine
Lymphocyte Count
Lymphocytes - immunology
Lymphocytes - metabolism
Mental health
Mental illness
Middle Aged
Pathology
Stress, Psychological - blood
Stress, Psychological - epidemiology
Stress, Psychological - immunology
Women
Young Adult
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Zusammenfassung:Psychoimmune interactions were studied in women of reproductive age with endometriosis. Pronounced immunological shifts manifested in a shift of the T-cellular immunity, resulting in imbalanced production of pro- (IL-1β, IL-2, IFN-γ) and anti-inflammatory (IL-4) cytokines. Significant correlations between the severity of mental shifts and immunopathogenetic factors in the studied patient population demonstrated the psychoneuroimmune nature of endometriosis.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-011-1463-0