Early Detection of Coronary Artery Flow and Myocardial Perfusion Impairment in Hypertensive Patients Evidenced by Myocardial Blush Grade (MBG) and Thrombolysis in Myocardial Infarction (TIMI) Frame Count (TFC)

Objective In hypertensive patients with typical chest pain but absence of coronary stenosis the coronary microcirculation may be impaired, thus, our study aimed to appraise, in these subjects, the role of the coronary microcirculation, assessed by Myocardial Blush Grade (MBG) and Thrombolysis in Myo...

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Veröffentlicht in:Internal Medicine 2012, Vol.51(13), pp.1653-1660
Hauptverfasser: Evola, Salvatore, Cuttitta, Francesco, Evola, Giovanna, Macaione, Francesca, Piraino, Davide, Meschisi, Maria Cristina, Peritore, Angelica, Lisi, Daniela Di, Novo, Guiseppina, Novo, Salvatore
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Sprache:eng
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Zusammenfassung:Objective In hypertensive patients with typical chest pain but absence of coronary stenosis the coronary microcirculation may be impaired, thus, our study aimed to appraise, in these subjects, the role of the coronary microcirculation, assessed by Myocardial Blush Grade (MBG) and Thrombolysis in Myocardial Infarction (TIMI) Frame Count (TFC). Methods A total of 95 subjects with chest pain and uninjured coronary arteries were recruited into the study: 80 subjects were hypertensive while 15 subjects were normotensive. The hypertensive subjects were divided into two subgroups: hypertensive subjects with positive scintigraphy and hypertensive subjects with negative scintigraphy. The TFC, a quantitative method of assessing coronary artery flow, the MBG, an assessment of the level of tissue perfusion, and the Total Myocardial Blush Score (TMBS), the sum of the myocardial blush grades of each coronary territory, were evaluated on the coronary angiogram of every patient. Results The TFC was higher (p
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.51.7385