Fatal anthrax infection in a heroin user from southern Germany, June 2012

Blood cultures from a heroin user who died in June 2012, a few hours after hospital admission, due to acute septic disease, revealed the presence of Bacillus anthracis. This report describes the extended diagnosis by MALDI-TOF and real-time PCR and rapid confirmation of the anthrax infection through...

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Veröffentlicht in:	Euro surveillance : bulletin européen sur les maladies transmissibles 2012-06, Vol.17 (26), p.1
Hauptverfasser:	Holzmann, T, Frangoulidis, D, Simon, M, Noll, P, Schmoldt, S, Hanczaruk, M, Grass, G, Pregler, M, Sing, A, Hörmansdorfer, S, Bernard, H, Grunow, R, Zimmermann, R, Schneider-Brachert, W, Gessner, A, Reischl, U
Format:	Artikel
Sprache:	eng
Schlagworte:	Anthrax Anthrax - diagnosis Anthrax - etiology Bacillus anthracis - genetics Bacillus anthracis - isolation & purification Bacteremia - etiology Bacterial infections Drug Contamination Drug use Drug Users Fatal Outcome Genome, Bacterial Germany Heroin Humans Laboratories Male Middle Aged Polymerase chain reaction Public health Real-Time Polymerase Chain Reaction Sepsis - etiology Substance Abuse, Intravenous - complications
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Zusammenfassung:	Blood cultures from a heroin user who died in June 2012, a few hours after hospital admission, due to acute septic disease, revealed the presence of Bacillus anthracis. This report describes the extended diagnosis by MALDI-TOF and real-time PCR and rapid confirmation of the anthrax infection through reference laboratories. Physicians and diagnostic laboratories were informed and alerted efficiently through the reporting channels of German public health institutions, which is essential for the prevention of further cases.
ISSN:	1560-7917 1025-496X 1560-7917
DOI:	10.2807/ese.17.26.20204-en