Optimized serodiagnosis of Mycoplasma pneumoniae infections

Abstract Serologic methods are well established for the diagnosis of Mycoplasma pneumoniae infections in humans, but they are less sensitive than polymerase chain reaction (PCR). To improve their sensitivity, a new panel of antigens was tested. Compared with PCR results, up to 92% of PCR-positive pa...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Diagnostic microbiology and infectious disease 2012-06, Vol.73 (2), p.200-203
Hauptverfasser: Dumke, Roger, Strubel, Andreas, Cyncynatus, Camille, Nuyttens, Hélène, Herrmann, Richard, Lück, Christian, Jacobs, Enno
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Abstract Serologic methods are well established for the diagnosis of Mycoplasma pneumoniae infections in humans, but they are less sensitive than polymerase chain reaction (PCR). To improve their sensitivity, a new panel of antigens was tested. Compared with PCR results, up to 92% of PCR-positive patients were confirmed by our immunoblotting approach having a specificity between 92.6% and 100%.
ISSN:0732-8893
1879-0070
DOI:10.1016/j.diagmicrobio.2012.02.014