2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Chemistry, and Bioactive Natural Products

A study investigated the solution-phase synthesis of 2,5-diketopiperazines, focusing on its molecular and chemical structures. Researchers made use of nuclear magnetic resonance (NMR) to study the synthesis, reactions and chemistry of 2-5-diketopiperazines.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical reviews 2012-07, Vol.112 (7), p.3641-3716
1. Verfasser:	Borthwick, Alan D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Products - chemical synthesis Biological Products - chemistry Biological Products - pharmacology Catalysis Cell Line, Tumor Chemical reactions Chemical synthesis Chemistry Techniques, Synthetic - methods Chemistry, Pharmaceutical - methods Crystal structure Diketopiperazines - chemical synthesis Diketopiperazines - chemistry Diketopiperazines - pharmacology Humans Molecular structure Natural products NMR Nuclear magnetic resonance Peptides Peptidomimetics - chemical synthesis Peptidomimetics - chemistry Peptidomimetics - pharmacology
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Beschreibung
Zusammenfassung:	A study investigated the solution-phase synthesis of 2,5-diketopiperazines, focusing on its molecular and chemical structures. Researchers made use of nuclear magnetic resonance (NMR) to study the synthesis, reactions and chemistry of 2-5-diketopiperazines.
ISSN:	0009-2665 1520-6890
DOI:	10.1021/cr200398y