Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions

Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions

A sensitive biosensor: A strategy for the intracellular imaging of Cu2+ ions has been developed by integrating a recognition molecule, N‐(2‐aminoethyl)‐N,N,N′tris(pyridin‐2‐ylmethyl)ethane‐1,2‐diamine (AE‐TPEA), into a hybrid system composed of carbon and CdSe/ZnS quantum dots.

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Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie International Edition 2012-07, Vol.51 (29), p.7185-7189
Hauptverfasser: Zhu, Anwei, Qu, Qiang, Shao, Xiangling, Kong, Biao, Tian, Yang
Format: Artikel
Sprache:eng
Schlagworte:
analytical methods
Biosensing Techniques - methods
Cadmium Compounds - chemistry
carbon
Carbon - chemistry
Cations, Divalent - analysis
copper
Copper - analysis
Ethylenediamines - chemistry
fluorescence spectroscopy
Fluorescent Dyes - chemistry
HeLa Cells
Humans
imaging agents
Pyridines - chemistry
Quantum Dots
Selenium Compounds - chemistry
Spectrometry, Fluorescence - methods
Sulfides - chemistry
Zinc Compounds - chemistry
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Zusammenfassung:A sensitive biosensor: A strategy for the intracellular imaging of Cu2+ ions has been developed by integrating a recognition molecule, N‐(2‐aminoethyl)‐N,N,N′tris(pyridin‐2‐ylmethyl)ethane‐1,2‐diamine (AE‐TPEA), into a hybrid system composed of carbon and CdSe/ZnS quantum dots.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201109089