Biocompatible Poly(L-lactide)/MWCNT Nanocomposites: Morphological Characterization, Electrical Properties, and Stem Cell Interaction

The promising perspectives of PLLA‐based nanostructured biomaterials and their relevance in tissue engineering are reported. Nanocomposites based on PLLA and MWCNTs are developed with an MWCNT content ranging from 0 to 3 wt%. The electrical properties show a percolation threshold within a range of 0.21–0.33 wt% MWCNTs, and the conductivity increases by six orders of magnitude. The surface structure shows changes with the carbon nanotube concentration. The functional role of MWCNTs incorporation in terms of interactions with adult stem cells suggests that PLLA/MWCNT nanocomposites are suitable substrates for primary stem cell culture. The design and preparation of PLLA‐based nanostructured biodegradable materials represent a perspective strategy in order to develop innovative multifunctional biomaterials, able to promote the interaction with human bone marrow stem cells, and it promises an exciting future at the interface of chemistry, biology, and material science.