Optimization of thromboelastography-guided platelet transfusion in cardiovascular surgery

Optimization of thromboelastography-guided platelet transfusion in cardiovascular surgery

Objectives Platelet dysfunction is a major cause of bleeding complications in patients undergoing cardiovascular surgery under cardiopulmonary bypass (CPB). Thromboelastography (TEG) can be used to assess post-CPB coagulopathy, but its utility in guiding platelet transfusion (PT) after CPB is unclea...

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Veröffentlicht in:General thoracic and cardiovascular surgery 2012-07, Vol.60 (7), p.411-416
Hauptverfasser: Aoki, Kenji, Sugimoto, Ai, Nagasawa, Ayako, Saito, Masayuki, Ohzeki, Hajime
Format: Artikel
Sprache:eng
Schlagworte:
Aneurysms
Aortic dissection
Blood Loss, Surgical - prevention & control
Blood platelets
Cardiac Surgery
Cardiac Surgical Procedures - adverse effects
Cardiology
Cardiopulmonary Bypass - adverse effects
Chi-Square Distribution
Heart surgery
Humans
Hypothermia
Japan
Medicine
Medicine & Public Health
Monitoring, Intraoperative - methods
Original Article
Patients
Platelet Count
Platelet Transfusion
Predictive Value of Tests
Surgeons
Surgical Oncology
Thoracic Surgery
Thrombelastography
Vascular Surgical Procedures - adverse effects
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Zusammenfassung:Objectives Platelet dysfunction is a major cause of bleeding complications in patients undergoing cardiovascular surgery under cardiopulmonary bypass (CPB). Thromboelastography (TEG) can be used to assess post-CPB coagulopathy, but its utility in guiding platelet transfusion (PT) after CPB is unclear. This study assessed the utility of a TEG-guided PT protocol in patients undergoing cardiovascular surgery under CPB. Methods The platelet count and TEG maximum amplitude (MA) was measured in 100 patients undergoing valvular or thoracic aortic surgery under CPB. PTs were guided by an empiric protocol in 50 patients (group C) and by a TEG-guided protocol (MA
ISSN:1863-6705
1863-6713
DOI:10.1007/s11748-012-0070-y