Diagnostic value of ADC in patients with prostate cancer: influence of the choice of b values
Objectives To evaluate the influence of the choice of b values on the diagnostic value of the apparent diffusion coefficient (ADC) for detection and grading of prostate cancer (PCa). Methods Forty-one patients with biopsy-proven PCa underwent endorectal 3-T MRI before prostatectomy. Different combin...
Gespeichert in:
| Veröffentlicht in: | European radiology 2012-08, Vol.22 (8), p.1820-1828 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | Objectives
To evaluate the influence of the choice of
b
values on the diagnostic value of the apparent diffusion coefficient (ADC) for detection and grading of prostate cancer (PCa).
Methods
Forty-one patients with biopsy-proven PCa underwent endorectal 3-T MRI before prostatectomy. Different combinations of
b
values (0–800 s/mm
2
) were used to calculate four representative ADC maps. Mean ADCs of tumours and non-malignant tissue were determined. Tumour appearance on different ADC maps was rated by three radiologists as good, fair or poor by assigning a visual score (VS) of 2, 1 or 0, respectively. Differences in the ADC values with the choice of
b
values were analysed using one-way ANOVA.
Results
Choice of
b
values had a highly (
P
|
|---|---|
| ISSN: | 0938-7994 1432-1084 |
| DOI: | 10.1007/s00330-012-2432-3 |