A feasible shortcut for the mobilization outcome: Steady state CD34 positive hematopoietic stem cells

Abstract Predicting success of hematopoietic cell mobilization is an important issue for transplant physicians. We examined the steady state peripheral blood CD34+ cell count to predict ability to mobilize adequate hematopoietic progenitor cells in 63 myeloma and lymphoma patients. The median steady...

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Veröffentlicht in:Transfusion and apheresis science 2012-08, Vol.47 (1), p.67-75
Hauptverfasser: Yüksel, Meltem Kurt, Tekgündüz, Emre, Sönmez, Çigdem, Topcuoglu, Pervin, Yurtcu, Arzu, Demiriz, Itır, Tetik, Ayşegül, Kayıkçı, Ömür, Cınarsoy, Murat, Altuntaş, Fevzi
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Sprache:eng
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Zusammenfassung:Abstract Predicting success of hematopoietic cell mobilization is an important issue for transplant physicians. We examined the steady state peripheral blood CD34+ cell count to predict ability to mobilize adequate hematopoietic progenitor cells in 63 myeloma and lymphoma patients. The median steady state CD34+ cell number was 1.56/μL (0.03–5.76). Although counting steady state CD34+ is definitely cost effective to predict the successful mobilization, we could not find a threshold steady state CD34 count of any value predicting successful mobilization.
ISSN:1473-0502
1878-1683
DOI:10.1016/j.transci.2012.05.003