Bilateral choroidal detachment after cord blood stem cell transplantation in an adult patient with acute myeloid leukemia

We report on bilateral choroidal detachment after a cord blood stem cell transplantation procedure. A 52-year-old woman had graft-versus-host disease 49 days after CBSCT for acute myeloid leukemia. She developed bilateral conjunctival chemosis and choroidal detachment 66 days after CBSCT. The annula...

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Veröffentlicht in:	International ophthalmology 2012-08, Vol.32 (4), p.379-381
Hauptverfasser:	Mimura, Tatsuya, Nakashizuka, Takayuki, Kami, Junko, Kohmura, Morio, Sato, Shimpei, Dou, Kazuhiro, Mori, Mikiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Case Report Choroid Diseases - etiology Cord Blood Stem Cell Transplantation - adverse effects Fatal Outcome Female Graft vs Host Disease - complications Humans Leukemia, Myeloid, Acute - therapy Medicine Medicine & Public Health Middle Aged Ophthalmology Retinal Detachment - etiology
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Zusammenfassung:	We report on bilateral choroidal detachment after a cord blood stem cell transplantation procedure. A 52-year-old woman had graft-versus-host disease 49 days after CBSCT for acute myeloid leukemia. She developed bilateral conjunctival chemosis and choroidal detachment 66 days after CBSCT. The annular choroidal detachment gradually increased in both eyes, with no improvement noted over the following month. At 106 days after CBSCT, the patient died from multiple organ failure. Graft-versus-host disease can be associated with bilateral choroidal detachment after CBSCT.
ISSN:	0165-5701 1573-2630
DOI:	10.1007/s10792-012-9539-z