Histopathological and immunohistochemical study of laterocervical lymph node metastases of unknown primary origin

In this study, we examined histopathologically and immunohistochemically 24 cases of laterocervical lymph node metastases with unknown primary origin. For immunohistochemical study, we used a large panel of antibodies represented by CK7, CK19, CK20, CKAE1/AE3, CK34betaE12, TTF1, HBME-1, CEA, MUC5AC...

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Veröffentlicht in:	Romanian journal of morphology and embryology 2012, Vol.53 (2), p.337-342
Hauptverfasser:	Mălin, Ramona Denise, Ioniţă, Elena, Osman, I, Mogoantă, Carmen Aurelia, Cioroianu, Luminiţa, Ciolofan, S, Anghelina, F, Enăchescu, Mădălina
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - surgery Female Humans Immunohistochemistry Lymph Node Excision Lymph Nodes - metabolism Lymph Nodes - pathology Lymph Nodes - surgery Lymphatic Metastasis Male Middle Aged Neoplasm Staging Neoplasms - metabolism Neoplasms - pathology Neoplasms - surgery Neoplasms, Unknown Primary - metabolism Neoplasms, Unknown Primary - pathology Neoplasms, Unknown Primary - surgery
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Zusammenfassung:	In this study, we examined histopathologically and immunohistochemically 24 cases of laterocervical lymph node metastases with unknown primary origin. For immunohistochemical study, we used a large panel of antibodies represented by CK7, CK19, CK20, CKAE1/AE3, CK34betaE12, TTF1, HBME-1, CEA, MUC5AC and EBV. In the cases studied tumors accompanied by seemingly primitive adenopathies were located in the thyroid, lung, esophagus, stomach, rhinopharynx, hypopharynx, oropharynx and larynx.
ISSN:	1220-0522