Cutaneous sarcoidosis in a patient with ulcerative colitis on infliximab

The advance of anti-tumour necrosis factor (TNF) therapy had dramatically changed the treatment algorithm of inflammatory bowel disease (IBD). This had significantly improved the quality of life for patients with Crohn's disease (CD) and ulcerative colitis (UC).1 However, side-effects of anti-T...

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Veröffentlicht in:	Journal of Crohn's and colitis 2012-07, Vol.6 (6), p.708-712
Hauptverfasser:	Fok, Kum C., Ng, Watson W.S., Henderson, Christopher J.A., Connor, Susan J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anti-Inflammatory Agents - adverse effects Anti-Inflammatory Agents - therapeutic use Antibodies, Monoclonal - adverse effects Antibodies, Monoclonal - therapeutic use Colitis, Ulcerative - complications Colitis, Ulcerative - drug therapy Female Humans Infliximab Sarcoidosis Sarcoidosis - chemically induced Sarcoidosis - diagnosis Side-effects Skin Diseases - chemically induced Skin Diseases - diagnosis Ulcerative colitis
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Beschreibung
Zusammenfassung:	The advance of anti-tumour necrosis factor (TNF) therapy had dramatically changed the treatment algorithm of inflammatory bowel disease (IBD). This had significantly improved the quality of life for patients with Crohn's disease (CD) and ulcerative colitis (UC).1 However, side-effects of anti-TNF treatment were unavoidable with paradoxical inflammation (for example leucocytoclastic vasculitis and psoriasis) being well-known phenomena of anti-TNF therapy.2 We report a case of infliximab induced cutaneous sarcoidosis in a patient with ulcerative colitis and review the literature.
ISSN:	1873-9946 1876-4479
DOI:	10.1016/j.crohns.2012.01.008