Factors influencing adherence to antiretroviral treatment in Asian developing countries: a systematic reviewRevue systematique: Facteurs influencant l'adhesion au traitement antiretroviral dans les pays asiatiques en developpementRevision sistematica: Factores que influyen en la adherencia al tratamiento antirretroviral en paises asiaticos en vias de desarrollo

Objective To systematically review the literature of factors affecting adherence to Antiretroviral treatment (ART) in Asian developing countries. Methods Database searches in Medline/Ovid, Cochrane library, CINAHL, Scopus and PsychINFO for studies published between 1996 and December 2010. The reference lists of included papers were also checked, with citation searching on key papers. Results A total of 437 studies were identified, and 18 articles met the inclusion criteria and were extracted and critically appraised, representing in 12 quantitative, four qualitative and two mixed-method studies. Twenty-two individual themes, including financial difficulties, side effects, access, stigma and discrimination, simply forgetting and being too busy, impeded adherence to ART, and 11 themes, including family support, self-efficacy and desire to live longer, facilitated adherence. Conclusion Adherence to ART varies between individuals and over time. We need to redress impeding factors while promoting factors that reinforce adherence through financial support, better accessible points for medicine refills, consulting doctors for help with side effects, social support and trusting relationships with care providers.Original Abstract: Objectif: Examiner systematiquement la litterature sur les facteurs influencant l'adhesion au traitement ARV (TARV) dans les pays asiatiques en developpement. Methodes: Recherche dans les bases de donnees Medline/Ovid, Cochrane Library, CINAHL, Scopus et PsychINFO pour des etudes publiees entre 1996 et decembre 2010. Les listes de references des articles cites ont egalement ete verifiees, avec la recherche des citations d'articles cles. Resultats: Au total 437 etudes ont ete identifiees, 18 articles ont repondu aux criteres d'inclusion et ont ete extraits et evalues de facon critique, ce qui represente 12 etudes quantitatives, 4 qualitatives et 2 a methodes mixtes. 31 themes differents comprenant les difficultes financieres, les effets secondaires, l'acces, la stigmatisation et la discrimination, le simple oubli et le fait d'etre trop occupe, entravaient l'adhesion au TARV, et 11 themes comprenant le soutien familial, l'auto-efficacite et le desir de vivre plus longtemps, facilitaient l'adhesion. Conclusion: L'adhesion au TARV varie selon les individus et dans le temps. Il est necessaire d'abaisser les facteurs entravant l'adhesion tout en favorisant ceux la renforcant, a travers un soutien financier, de meilleurs points d'acces pour la c