Long-term cardiac follow-up of children treated with anthracycline doses of 300mg/m2 or less for acute lymphoblastic leukemia

Long-term cardiac follow-up of children treated with anthracycline doses of 300mg/m2 or less for acute lymphoblastic leukemia

Background The cardiotoxic effect of anthracyclines has been well described for moderate to high cumulative doses (>350mg/m2). However, the question of whether sub-clinical signs of cardiomyopathy may develop and progress over time in children receiving doses of

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Bibliographische Detailangaben
Veröffentlicht in:Pediatric blood & cancer 2010-03, Vol.54 (3), p.444-448
Hauptverfasser: Rathe, Mathias, Carlsen, Niels Lauritz Torp, Oxhoj, Henrik, Nielsen, Gunner
Format: Artikel
Sprache:eng
Schlagworte:
Acute lymphatic leukemia
Age
Anthracycline
Blood
Cancer
Cardiomyopathy
Chemotherapy
Children
Echocardiography
Heart
Risk factors
Ventricle
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Zusammenfassung:Background The cardiotoxic effect of anthracyclines has been well described for moderate to high cumulative doses (>350mg/m2). However, the question of whether sub-clinical signs of cardiomyopathy may develop and progress over time in children receiving doses of
ISSN:1545-5017
DOI:10.1002/pbc.22302