A case report of a 33-year chronic phase survivor of chronic myeloid leukemia

Here, we report a Philadelphia chromosome-positive chronic myeloid leukemia case with the longest chronic phase and overall survival to our knowledge ever reported in the medical literature. During the 33-year chronic phase, he was asymptomatic without any treatment and had normal blood cell values....

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Veröffentlicht in:	Medical oncology (Northwood, London, England) London, England), 2012-06, Vol.29 (2), p.1102-1104
Hauptverfasser:	Ji, Ou, Shen, Qun, Zhang, Ya-Cheng, Ji, Jian-Min, Zhu, Guang-Rong, Lin, Lin, Kong, Xiang-Tu, Xia, Wen, Jiang, Peng-Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Abl protein Adult BCR protein Blood cells Case Report Case reports Chronic myeloid leukemia Fusion protein Fusion Proteins, bcr-abl - genetics Hematology Humans Internal Medicine Leukemia Leukemia, Myelogenous, Chronic, BCR-ABL Positive - blood Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Leukemia, Myelogenous, Chronic, BCR-ABL Positive - mortality Male Medicine Medicine & Public Health Oncology Pathology Philadelphia Chromosome Survivors Young Adult
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Beschreibung
Zusammenfassung:	Here, we report a Philadelphia chromosome-positive chronic myeloid leukemia case with the longest chronic phase and overall survival to our knowledge ever reported in the medical literature. During the 33-year chronic phase, he was asymptomatic without any treatment and had normal blood cell values. BCR – ABL silencing might be referred to the uncommon long-term survivor.
ISSN:	1357-0560 1559-131X
DOI:	10.1007/s12032-011-9874-3