ReGAE 7: long-term outcomes of augmented trabeculectomy with mitomycin C in African Caribbean patients

Background: To evaluate long‐term outcomes and complication rates following trabeculectomy with mitomycin C in a case series of African Caribbean patients. Design: A prospective, observational and non‐comparative case series. Participants: Forty‐seven consecutive African Caribbean patients (47 eyes) with glaucoma. Methods: All patients underwent augmented trabeculectomy with mitomycin C for uncontrolled intraocular pressure (IOP). Survival analysis was performed with a minimum of 12 months' follow up. Main Outcome Measures: Surgical success was based upon IOP reduction to ≤21 mmHg, ≤18 mmHg and ≤15 mmHg without glaucoma medication (complete); or IOP reduction to ≤21 mmHg, ≤18 mmHg and ≤15 mmHg with or without glaucoma medication (qualified). Results: The mean follow‐up period was 48.6 months. At 3 years post‐trabeculectomy 92.6% achieved a qualified success and 59.3% a complete success for an IOP ≤21 mmHg. At final follow up the mean IOP reduced from 33.7 mmHg to 13.1 mmHg (P