Carpal tunnel syndrome as an initial manifestation in a case of transthyretin-related familial amyloid polyneuropathy with a novel A120T mutation

Rt: right; Lt: left; DL: distal latency; CV: conduction velocity; CMAP: compound muscle action potential amplitude; Freq: frequency; Lat: latency; SNAP: sensory nerve action potential amplitude. 1 Introduction Transthyretin-related familial amyloid polyneuropathy (TTR-FAP) is an autosomal dominant disorder, involving the peripheral nervous system and visceral organs [1]. [...]this therapy can be applied only to patients below 60 years of age in many countries including Japan. [...]new therapeutic strategies are desirable.