Insulin-Like Growth Factors in Normal and Diseased Kidney

This article reviews the physiology of the insulin-like growth factor (IGF) system in the kidney and the changes and potential role of this system in selected renal diseases. The potential therapeutic uses of recombinant human IGF-I for the treatment of acute and chronic kidney failure are briefly d...

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Veröffentlicht in:	Endocrinology and metabolism clinics of North America 2012-06, Vol.41 (2), p.351-374
Hauptverfasser:	Kiepe, Daniela, MD, Tönshoff, Burkhard, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Endocrinology & Metabolism Humans IGF-system Insulin-Like Growth Factor Binding Proteins - physiology Kidney - metabolism Kidney disease Kidney Diseases - drug therapy Kidney Diseases - metabolism Mice Pathophysiology Rats Somatomedins - physiology Somatomedins - therapeutic use Treatment
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Beschreibung
Zusammenfassung:	This article reviews the physiology of the insulin-like growth factor (IGF) system in the kidney and the changes and potential role of this system in selected renal diseases. The potential therapeutic uses of recombinant human IGF-I for the treatment of acute and chronic kidney failure are briefly discussed.
ISSN:	0889-8529 1558-4410
DOI:	10.1016/j.ecl.2012.04.015