Pulmonary function and long-term follow-up of children with tracheobronchomalacia
Background Primary tracheobronchomalacia (TBM) is a disease of the large airways. Long‐term follow‐up studies of TBM patients have not been reported. This study was undertaken to further elicit the natural history of this condition and the presence of concomitant reactive airways disease through cli...
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Veröffentlicht in: | Pediatric pulmonology 2012-07, Vol.47 (7), p.700-705 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Background
Primary tracheobronchomalacia (TBM) is a disease of the large airways. Long‐term follow‐up studies of TBM patients have not been reported. This study was undertaken to further elicit the natural history of this condition and the presence of concomitant reactive airways disease through clinical profiling and pulmonary function testing.
Methods
Twenty‐one children diagnosed with TBM by bronchoscopy between 1998 and 2001 in Queensland were recruited in 2008. Parents completed a questionnaire detailing their child's respiratory symptoms over the previous 12 months. Children then undertook pulmonary function and flow–volume loop classification. Mannitol bronchial provocation testing or post‐bronchodilator spirometry was performed to assess for the confounding presence of reactive airways disease.
Results
Data from 19 children (12 males) were able to be analyzed. The median age was 9.4 (range 7.6–14.3) years. 15 parents indicated their child's symptoms were unresolved. The mean FEV1 was 81% predicted with 7 |
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ISSN: | 8755-6863 1099-0496 |
DOI: | 10.1002/ppul.21612 |