Prognostic significance of SUVmax (maximum standardized uptake value) measured by [18F]FDG PET/CT in endometrial cancer

Purpose To determine if the preoperative maximum standardized uptake value (SUVmax) measured by [ 18 F]FDG PET/CT has prognostic value in patients with endometrial cancer. Methods A total of 57 patients with FIGO stage I–IV endometrial cancer underwent FDG PET/CT imaging before radical surgery. SUVm...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2012-05, Vol.39 (5), p.840-845
Hauptverfasser:	Kitajima, Kazuhiro, Kita, Masato, Suzuki, Kayo, Senda, Michio, Nakamoto, Yuji, Sugimura, Kazuro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological Transport Cancer Cardiology Computed tomography Disease-Free Survival Endometrial cancer Endometrial Neoplasms - diagnostic imaging Endometrial Neoplasms - pathology Endometrium Female Fluorodeoxyglucose F18 - metabolism Humans Imaging Lymph nodes Medical imaging Medicine Medicine & Public Health Metastases Middle Aged Multimodal Imaging Multivariate analysis myometrium Nuclear Medicine Oncology Original Article Orthopedics Positron-Emission Tomography Radicals Radiology Recurrence Retrospective Studies Surgery Survival Tomography, X-Ray Computed Tumors
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Zusammenfassung:	Purpose To determine if the preoperative maximum standardized uptake value (SUVmax) measured by [ 18 F]FDG PET/CT has prognostic value in patients with endometrial cancer. Methods A total of 57 patients with FIGO stage I–IV endometrial cancer underwent FDG PET/CT imaging before radical surgery. SUVmax of the primary tumour was compared with histological prognostic factors, and the relationship between SUVmax and recurrence was examined. Results The median duration of follow-up was 33.1 months (range 4 to 68 months). SUVmax was significantly higher in patients with a higher FIGO stage ( p = 0.0015), higher tumour histological grade ( p
ISSN:	1619-7070 1619-7089
DOI:	10.1007/s00259-011-2057-9