Clinical implications and prognostic significance of thrombocytopenia in Tunisian patients with systemic lupus erythematosus

Clinical implications and prognostic significance of thrombocytopenia in Tunisian patients with systemic lupus erythematosus

Objective: The objective of this study was to determine the role of thrombocytopenia in terms of disease manifestations, disease activity and prognostic impact in a cohort of Tunisian systemic lupus erythematosus (SLE) patients. Methods: The charts of 182 SLE patients diagnosed between 1996 and 2009...

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Veröffentlicht in:Lupus 2012-05, Vol.21 (6), p.682-687
Hauptverfasser: Jallouli, M, Frigui, M, Marzouk, S, Snoussi, M, Kechaou, M, Kaddour, N, Masmoudi, H, Elloumi, M, Bahloul, Z
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Antibodies
Anticoagulants
Binding sites
Case-Control Studies
Cohort Studies
Enzymes
Female
Follow-Up Studies
Hemorrhage
Humans
Internal medicine
Kidney
Kidney diseases
Logistic Models
Lupus
Lupus Erythematosus, Systemic - diagnosis
Lupus Erythematosus, Systemic - epidemiology
Lupus Erythematosus, Systemic - physiopathology
Male
Medical prognosis
Mortality
Multivariate analysis
Prognosis
Regression analysis
Retrospective Studies
Severity of Illness Index
Splenomegaly
Statistical analysis
Survival
Survival Rate
Systemic lupus erythematosus
Thrombocytopenia
Thrombocytopenia - diagnosis
Thrombocytopenia - epidemiology
Thrombocytopenia - physiopathology
Thrombosis
Tunisia
Variables
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Zusammenfassung:Objective: The objective of this study was to determine the role of thrombocytopenia in terms of disease manifestations, disease activity and prognostic impact in a cohort of Tunisian systemic lupus erythematosus (SLE) patients. Methods: The charts of 182 SLE patients diagnosed between 1996 and 2009 were retrospectively reviewed. The clinical manifestations, immunological profiles, disease activity, SLE relapses and survival rate at the time of follow-up were recorded. Results: Thrombocytopenia (
ISSN:0961-2033
1477-0962
DOI:10.1177/0961203312438630