The schizoictal syndrome

Abstract There are several common denominators of schizophrenia and epilepsy including models of pathogenesis as well as their clinical occurence mainly referring to schizophrenia-like syndrome in epilepsy or similar clinical entities [1] . Up to now it has not been emphasized that a process of synchronization or desynchronization of neuronal cell structures within the context of neuronal plasticity might be a plausible pathogenetic mechanism of epilepsy as well as schizophrenia. Clinical as well as therapeutical implications of this hypothesis on the basis of scientific evidence are discussed.