Tooth whitening with hydrogen/carbamide peroxides in association with a CPP-ACP paste at different proportions

Background: Different enhanced peroxide formulations have been developed to overcome mineral loss during tooth whitening. This study investigated the impact on tooth whitening from combining a CPP‐ACP paste with home peroxide agents at several proportions. Methods: Ninety bovine incisors were randomly allocated into nine groups (n = 10) and exposed to 7.5% hydrogen peroxide (HP), 16% carbamide peroxide (CP), a CPP‐ACP paste (Tooth Mousse/MI Paste, GC Corporation, Tokyo, Japan) and blends of HP/CP:MI at three proportions (1:1, 2:1 and 1:2). Tooth whitening was performed for 14 days and its effectiveness was measured by a spectrophotometer utilizing the CIE L*a*b* system (ΔE, ΔL*, Δa* and Δb*). Colour readings were measured at baseline (T0), 7 days of bleaching (T7), 14 days of bleaching (T14) and 7 days after the end of bleaching (T21). Data were analysed by two‐way ANOVA for paired averages followed by the Tukey’s test and Pearson’s correlation at 5%. Results: Although CP produced the greatest colour change (ΔE), all whitening protocols were considered to be effective regardless of the CPP‐ACP presence. In general, greater changes in ΔE, ΔL*, Δa* and Δb* were detected at T14, with T21 exhibiting similar results to those at T7. A greater number of strong correlations with ΔE values was found for a* (11/15). Conclusions: Within the limitations of this study, the results indicate that the CPP‐ACP paste did not affect tooth whitening efficacy.