Vascular Heterogeneity in the Kidney

Summary Blood vessels and their endothelial lining are uniquely adapted to the needs of the underlying tissue. The structure and function of the vasculature varies both between and within different organs. In the kidney, the vascular architecture is designed to function both in oxygen/nutrient deliv...

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Veröffentlicht in:	Seminars in nephrology 2012-03, Vol.32 (2), p.145-155
Hauptverfasser:	Molema, Grietje, PhD, Aird, William C., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arterioles - anatomy & histology Arterioles - physiology Capillaries - anatomy & histology Capillaries - physiology endothelial cells Endothelial Cells - physiology heterogeneity Humans Kidney Kidney - blood supply Kidney Glomerulus - blood supply Nephrology Renal Artery - anatomy & histology Renal Artery - physiology Renal Veins - anatomy & histology Renal Veins - physiology vasculature
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Beschreibung
Zusammenfassung:	Summary Blood vessels and their endothelial lining are uniquely adapted to the needs of the underlying tissue. The structure and function of the vasculature varies both between and within different organs. In the kidney, the vascular architecture is designed to function both in oxygen/nutrient delivery and filtration of blood according to the homeostatic needs of the body. Here, we review spatial and temporal differences in renal vascular phenotypes in both health and disease.
ISSN:	0270-9295 1558-4488
DOI:	10.1016/j.semnephrol.2012.02.001