Needs for an Expanded Ontology-Based Classification of Adverse Drug Reactions and Related Mechanisms
The growing significance of bioinformatics and systems biology in drug safety research requires a system of adverse‐event classification that goes beyond a simple vocabulary. This opinion piece outlines the need for development of an ontology‐based framework of describing adverse drug reactions (ADR...
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| Veröffentlicht in: | Clinical pharmacology and therapeutics 2012-06, Vol.91 (6), p.963-965 |
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| container_title | Clinical pharmacology and therapeutics |
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| creator | Zhichkin, P E Athey, B D Avigan, M I Abernethy, D R |
| description | The growing significance of bioinformatics and systems biology in drug safety research requires a system of adverse‐event classification that goes beyond a simple vocabulary. This opinion piece outlines the need for development of an ontology‐based framework of describing adverse drug reactions (ADRs) and describes the potential applications for such a framework.
Clinical Pharmacology & Therapeutics (2012); 91 6, 963–965. doi:10.1038/clpt.2012.41 |
| doi_str_mv | 10.1038/clpt.2012.41 |
| format | Article |
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| ispartof | Clinical pharmacology and therapeutics, 2012-06, Vol.91 (6), p.963-965 |
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| language | eng |
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| source | MEDLINE; Wiley Online Library All Journals |
| subjects | Bayes Theorem Classification Clinical Trials as Topic Computational Biology Databases, Factual Drug-Related Side Effects and Adverse Reactions - classification Humans Models, Organizational Pharmacovigilance Public Health Terminology as Topic |
| title | Needs for an Expanded Ontology-Based Classification of Adverse Drug Reactions and Related Mechanisms |
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