Effects of Lead Exposure on Growth and Bone Biology in Growing Rats Exposed to Simulated High Altitude

Effects of Lead Exposure on Growth and Bone Biology in Growing Rats Exposed to Simulated High Altitude

The existence of children living at high altitude suffering from lead (Pb) poisoning prompted us to investigate the long term effects of this pollutant on growth and bone biology in growing rats maintained at simulated high altitude (SHA). Pb and hypoxia (HX) significantly reduced body weight (−9.4 ...

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Veröffentlicht in:Bulletin of environmental contamination and toxicology 2012-06, Vol.88 (6), p.1033-1037
Hauptverfasser: Conti, María Inés, Terrizzi, Antonela R., Lee, Ching Ming, Mandalunis, Patricia M., Bozzini, Clarisa, Piñeiro, Adriana E., Martínez, María del Pilar
Format: Artikel
Sprache:eng
Schlagworte:
Absorption
Altitude
Animals
Aquatic Pollution
Body weight
Bone and Bones - drug effects
Bone and Bones - physiology
Bone Development - drug effects
Bones
Earth and Environmental Science
Ecotoxicology
Environment
Environmental Chemistry
Environmental Health
Environmental Pollutants - toxicity
Female
Growth and Development - drug effects
Hypoxia
Lead
Lead - toxicity
Lead poisoning
Physical growth
Pollution
Rats
Rats, Wistar
Rodents
Soil Science & Conservation
Toxicity
Waste Water Technology
Water Management
Water Pollution Control
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Zusammenfassung:The existence of children living at high altitude suffering from lead (Pb) poisoning prompted us to investigate the long term effects of this pollutant on growth and bone biology in growing rats maintained at simulated high altitude (SHA). Pb and hypoxia (HX) significantly reduced body weight (−9.4 % and −24 %; p  
ISSN:0007-4861
1432-0800
DOI:10.1007/s00128-012-0602-2