Effect of Vitamin D Repletion on Urinary Calcium Excretion among Kidney Stone Formers

Despite the important role of vitamin D in maintaining bone health, many clinicians are reluctant to treat vitamin D deficiency in kidney stone formers because of the theoretical risk of increasing urinary calcium excretion. This study examined the effect of vitamin D repletion on urinary calcium ex...

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Veröffentlicht in:	Clinical journal of the American Society of Nephrology 2012-05, Vol.7 (5), p.829-834
Hauptverfasser:	Leaf, David E, Korets, Ruslan, Taylor, Eric N, Tang, Jie, Asplin, John R, Goldfarb, David S, Gupta, Mantu, Curhan, Gary C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Calcium - urine Ergocalciferols - adverse effects Ergocalciferols - pharmacology Ergocalciferols - therapeutic use Female Humans Kidney Calculi - complications Kidney Calculi - urine Linear Models Male Middle Aged Multivariate Analysis Parathyroid Hormone - blood Sodium - urine Statistics, Nonparametric Vitamin D - analogs & derivatives Vitamin D - blood Vitamin D Deficiency - blood Vitamin D Deficiency - complications Vitamin D Deficiency - drug therapy Vitamins - adverse effects Vitamins - pharmacology Vitamins - therapeutic use
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Beschreibung
Zusammenfassung:	Despite the important role of vitamin D in maintaining bone health, many clinicians are reluctant to treat vitamin D deficiency in kidney stone formers because of the theoretical risk of increasing urinary calcium excretion. This study examined the effect of vitamin D repletion on urinary calcium excretion among stone formers. Participants (n=29) were recruited from urology clinics affiliated with New York Presbyterian Hospital. Enrollment criteria included a history of nephrolithiasis, urinary calcium excretion between 150 and 400 mg/d, and a serum 25-hydroxyvitamin D level
ISSN:	1555-9041 1555-905X
DOI:	10.2215/CJN.11331111