Relation of epicardial adipose tissue and carotid intima-media thickness in patients with nonalcoholic fatty liver disease

OBJECTIVECurrently, nonalcoholic fatty liver disease (NAFLD) itself has been accepted as an atherosclerotic risk factor and related to increased cardiovascular disease risk. In this study, we aimed to investigate the relationship of epicardial fat thickness (EFT), a parameter associated with atheros...

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Veröffentlicht in:	European journal of gastroenterology & hepatology 2012-06, Vol.24 (6), p.613-618
Hauptverfasser:	Colak, Yasar, Karabay, Can Yucel, Tuncer, Ilyas, Kocabay, Gonenc, Kalayci, Arzu, Senates, Ebubekir, Ozturk, Oguzhan, Doganay, Hamdi Levent, Enc, Feruze Yilmaz, Ulasoglu, Celal, Kiziltas, Safak
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - diagnostic imaging Adipose Tissue - pathology Adult Anthropometry - methods Biological and medical sciences Biopsy, Needle - methods Carotid Intima-Media Thickness Case-Control Studies Fatty Liver - diagnostic imaging Fatty Liver - pathology Female Gastroenterology. Liver. Pancreas. Abdomen Humans Liver - pathology Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Middle Aged Non-alcoholic Fatty Liver Disease Other diseases. Semiology Pericardium - diagnostic imaging Pericardium - pathology Ultrasonography, Interventional - methods Waist Circumference
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Zusammenfassung:	OBJECTIVECurrently, nonalcoholic fatty liver disease (NAFLD) itself has been accepted as an atherosclerotic risk factor and related to increased cardiovascular disease risk. In this study, we aimed to investigate the relationship of epicardial fat thickness (EFT), a parameter associated with atherosclerosis in recent years, with carotid artery intima-media thickness (C-IMT), another parameter of subclinical atherosclerosis. DESIGN AND METHODSWe investigated 57 patients with biopsy-proven NAFLD and 30 age-matched and sex-matched controls. EFT was obtained by transthoracic echocardiography and C-IMT was evaluated by an ultrasonographic measurement using a linear type B-mode probe. RESULTSEFT and C-IMT were significantly higher in NAFLD patients compared with the controls (EFT0.58±0.18 vs. 0.36±0.17 cm, P
ISSN:	0954-691X 1473-5687
DOI:	10.1097/MEG.0b013e3283513f19