Endocrine archeology: Do insects retain ancestrally inherited counterparts of the vertebrate releasing hormones GnRH, GHRH, TRH, and CRF?

Graphical abstract Highlights ► A nematodes peptide activates both the GnRH and the insect adipokinetic hormone (AKH) receptor. ► The very ancient ancestor of growth hormone releasing hormone (GHRH) may have been glucagon-like. ► A challenging hypothesis: juvenile hormone developed as ersatz for thy...

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Veröffentlicht in:	General and comparative endocrinology 2012-05, Vol.177 (1), p.18-27
Hauptverfasser:	Loof, Arnold De, Lindemans, Marleen, Liu, Feng, De Groef, Bert, Schoofs, Liliane
Format:	Artikel
Sprache:	eng
Schlagworte:	adipokinetic hormone AKH Animals Annelida Archaeology - methods arthropods bioinformatics corticotropin Corticotropin-Releasing Hormone - metabolism diuretic hormone Endocrinology & Metabolism energy metabolism genes GnRH Gonadotropin gonadotropin-releasing hormone Gonadotropin-Releasing Hormone - metabolism Growth Hormone-Releasing Hormone - metabolism hypothalamus Insect hormones Insecta juvenile hormones Juvenile Hormones - metabolism locusts Models, Biological molluscs Nematoda Neuropeptides phylogeny Releasing hormone somatoliberin thyroid hormones thyrotropin-releasing hormone Thyrotropin-Releasing Hormone - metabolism vertebrates water metabolism
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